1. Lin A, Elbezanti WO, Schirling A, Ahmed A, Van Duyne R, Cocklin S, et al. Alprazolam Prompts HIV-1 Transcriptional Reactivation and Enhances CTL Response Through RUNX1 Inhibition and STAT5 Activation. Front Neurol. 2021;12:663793.
2. Jones AD, Khakhina S, Jaison T, Santos E, Smith S, Klase ZA. CD8(+) T-Cell Mediated Control of HIV-1 in a Unique Cohort With Low Viral Loads. Front Microbiol. 2021;12:670016.
3. Li Y, Klase Z, Sardo L. Visualizing Chromatin Modifications in Isolated Nuclei. Methods Mol Biol. 2020;2175:23-31.
4. Fultang N, Illendula A, Lin J, Pandey MK, Klase Z, Peethambaran B. ROR1 regulates chemoresistance in Breast Cancer via modulation of drug efflux pump ABCB1. Sci Rep. 2020;10(1):1821.
5. Elbezanti W, Lin A, Schirling A, Jackson A, Marshall M, Duyne RV, et al. Benzodiazepines Drive Alteration of Chromatin at the Integrated HIV-1 LTR. Viruses. 2020;12(2).
6. Chen K, Phan T, Lin A, Sardo L, Mele AR, Nonnemacher MR, et al. Morphine exposure exacerbates HIV-1 Tat driven changes to neuroinflammatory factors in cultured astrocytes. PLoS One. 2020;15(3):e0230563.
7. Fultang N, Illendula A, Chen B, Wu C, Jonnalagadda S, Baird N, et al. Strictinin, a novel ROR1-inhibitor, represses triple negative breast cancer survival and migration via modulation of PI3K/AKT/GSK3ss activity. PLoS One. 2019;14(5):e0217789.
8. Mele AR, Marino J, Chen K, Pirrone V, Janetopoulos C, Wigdahl B, et al. Defining the molecular mechanisms of HIV-1 Tat secretion: PtdIns(4,5)P2 at the epicenter. Traffic. 2018.
9. Fultang N, Brar J, Mercier I, Klase Z, Peethambaran B. Myrothamnus flabellifolius selectively targets Triple Negative Breast Cancer in vitro, restoring Tamoxifen Sensitivity through modulation of miRNAs associated with Estrogen Receptors. International Journal of Applied Research in Natural Products. 2018;11(1).
10. Braun A, Farber MJ, Klase ZA, Berget PB, Myers KA. A cell surface display fluorescent biosensor for measuring MMP14 activity in real-time. Sci Rep. 2018;8(1):5916.
11. Sardo L, Lin A, Khakhina S, Beckman L, Ricon L, Elbezanti W, et al. Real-time visualization of chromatin modification in isolated nuclei. J Cell Sci. 2017;130(17):2926-40.
12. Sardo L, Vakil PR, Elbezanti W, El-Sayed A, Klase Z. The inhibition of microRNAs by HIV-1 Tat suppresses beta catenin activity in astrocytes. Retrovirology. 2016;13:25.
13. Sampey GC, Saifuddin M, Schwab A, Barclay R, Punya S, Chung MC, et al. Exosomes from HIV-1-infected Cells Stimulate Production of Pro-inflammatory Cytokines through Trans-activating Response (TAR) RNA. The Journal of biological chemistry. 2016;291(3):1251-66.
14. Ortiz AM, Klase ZA, DiNapoli SR, Vujkovic-Cvijin I, Carmack K, Perkins MR, et al. IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques. Mucosal immunology. 2016;9(2):458-67.
15. Lin A, Klase Z. A CRISPR Approach for Reactivating Latent HIV-1. Molecular therapy : the journal of the American Society of Gene Therapy. 2016;24(3):416-8.
16. Klase ZA, Khakhina S, Schneider Ade B, Callahan MV, Glasspool-Malone J, Malone R. Zika Fetal Neuropathogenesis: Etiology of a Viral Syndrome. PLoS neglected tropical diseases. 2016;10(8):e0004877.
17. Sardo L, Iordanskiy S, Klase Z, Kashanchi F. HIV-1 Nef blocks autophagy in human astrocytes. Cell Cycle. 2015;14(24):3781-2.
18. Klase Z, Ortiz A, Deleage C, Mudd JC, Quinones M, Schwartzman E, et al. Dysbiotic bacteria translocate in progressive SIV infection. Mucosal immunology. 2015;8(5):1009-20.
19. Barbian HJ, Li Y, Ramirez M, Klase Z, Lipende I, Mjungu D, et al. Destabilization of the gut microbiome marks the end-stage of simian immunodeficiency virus infection in wild chimpanzees. American journal of primatology. 2015.
20. Klase Z, Yedavalli VS, Houzet L, Perkins M, Maldarelli F, Brenchley J, et al. Activation of HIV-1 from latent infection via synergy of RUNX1 inhibitor Ro5-3335 and SAHA. PLoS pathogens. 2014;10(3):e1003997.
21. Calantone N, Wu F, Klase Z, Deleage C, Perkins M, Matsuda K, et al. Tissue Myeloid Cells in SIV-Infected Primates Acquire Viral DNA through Phagocytosis of Infected T Cells. Immunity. 2014;41(3):493-502.
22. Van Duyne R, Guendel I, Jaworski E, Sampey G, Klase Z, Chen H, et al. Effect of mimetic CDK9 inhibitors on HIV-1-activated transcription. Journal of molecular biology. 2013;425(4):812-29.
23. Tang S-W, Chen C-Y, Klase Z, Zane L, Jeang K-T. The cellular autophagy pathway modulates human T-cell leukemia virus type 1 replication. Journal of virology. 2013;87(3):1699-707.
24. Klase ZA, Sampey GC, Kashanchi F. Retrovirus infected cells contain viral microRNAs. Retrovirology. 2013;10(15):4690-10.
25. Klase ZA, Houzet L, Jeang K-T. Quantification of miRNA by Poly (A)-RT-qPCR Arrays and Verification of Target Sites in HIV-1 Using a One-LTR Infectious Molecular Clone. Human Retroviruses: Springer; 2013. p. 285-96.
26. Klase Z, Jeang KT. Reciprocal functional pseudotyping of HIV-1 and HTLV-1 viral genomes by the heterologous counterpart envelope proteins. Virology. 2013;443(1):106-12.
27. Van Duyne R, Guendel I, Klase Z, Narayanan A, Coley W, Jaworski E, et al. Localization and sub-cellular shuttling of HTLV-1 tax with the miRNA machinery. PloS one. 2012;7(7):e40662.
28. Sampey GC, Guendel I, Das R, Jaworski E, Klase Z, Narayanan A, et al. Transcriptional gene silencing (TGS) via the RNAi machinery in HIV-1 infections. Biology. 2012;1(2):339-69.
29. Klase Z, Houzet L, Jeang K-T. MicroRNAs and HIV-1: complex interactions. Journal of Biological Chemistry. 2012;287(49):40884-90.
30. Houzet L, Klase Z, Yeung ML, Wu A, Le S-Y, Quiñones M, et al. The extent of sequence complementarity correlates with the potency of cellular miRNA-mediated restriction of HIV-1. Nucleic acids research. 2012;40(22):11684-96.
31. Van Duyne R, Guendel I, Narayanan A, Gregg E, Shafagati N, Tyagi M, et al. Varying modulation of HIV-1 LTR activity by Baf complexes. Journal of molecular biology. 2011;411(3):581-96.
32. Klase Z, Houzet L, Jeang KT. Replication competent HIV-1 viruses that express intragenomic microRNA reveal discrete RNA-interference mechanisms that affect viral replication. Cell & bioscience. 2011;1(1):38.
33. Van Duyne R, Guendel I, Kehn-Hall K, Easley R, Klase Z, Liu C, et al. The identification of unique serum proteins of HIV-1 latently infected long-term non-progressor patients. AIDS research and therapy. 2010;7:21.
34. Easley R, Carpio L, Guendel I, Klase Z, Choi S, Kehn-Hall K, et al. Human T-lymphotropic virus type 1 transcription and chromatin-remodeling complexes. J Virol. 2010;84(9):4755-68.
35. Easley R, Carpio L, Dannenberg L, Choi S, Alani D, Van Duyne R, et al. Transcription through the HIV-1 nucleosomes: effects of the PBAF complex in Tat activated transcription. Virology. 2010;405(2):322-33.
36. Coley W, Van Duyne R, Carpio L, Guendel I, Kehn-Hall K, Chevalier S, et al. Absence of DICER in monocytes and its regulation by HIV-1. Journal of Biological Chemistry. 2010;285(42):31930-43.
37. Carpio L, Klase Z, Coley W, Guendel I, Choi S, Van Duyne R, et al. microRNA machinery is an integral component of drug-induced transcription inhibition in HIV-1 infection. Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research. 2010;6(1):386-400.
38. Zhou M, Huang K, Jung KJ, Cho WK, Klase Z, Kashanchi F, et al. Bromodomain protein Brd4 regulates human immunodeficiency virus transcription through phosphorylation of CDK9 at threonine 29. J Virol. 2009;83(2):1036-44.
39. Klase ZA, Jeang K-T, Kashanchi F. HIV-1 and RNA interference—examining a complex system. RNA Viruses: Host Gene Responses to Infections. 2009:83.
40. Klase Z, Winograd R, Davis J, Carpio L, Hildreth R, Heydarian M, et al. HIV-1 TAR miRNA protects against apoptosis by altering cellular gene expression. Retrovirology. 2009;6(1):18.
41. Wu W, Kehn-Hall K, Pedati C, Zweier L, Castro I, Klase Z, et al. Drug 9AA reactivates p21/Waf1 and Inhibits HIV-1 progeny formation. Virology journal. 2008;5:41.
42. Van Duyne R, Kehn-Hall K, Klase Z, Easley R, Heydarian M, Saifuddin M, et al. Retroviral proteomics and interactomes: intricate balances of cell survival and viral replication. Expert review of proteomics. 2008;5(3):507-28.
43. Van Duyne R, Easley R, Wu W, Berro R, Pedati C, Klase Z, et al. Lysine methylation of HIV-1 Tat regulates transcriptional activity of the viral LTR. Retrovirology. 2008;5(1):40.
44. Ku SC, Lee J, Lau J, Gurumurthy M, Ng R, Lwa SH, et al. XBP-1, a novel human T-lymphotropic virus type 1 (HTLV-1) tax binding protein, activates HTLV-1 basal and tax-activated transcription. Journal of virology. 2008;82(9):4343-53.
45. Klase ZA, Van Duyne R, Kashanchi F. Identification of potential drug targets using genomics and proteomics: a systems approach. Advances in pharmacology. 2008;56:327.
46. Kehn-Hall K, Berro R, Klase Z, Saifuddin M, Kashanchi F. Identifying membrane protein surface markers of HIV-1 infection. Future HIV Therapy. 2008;2(2):155-65.
47. Berro R, Pedati C, Kehn-Hall K, Wu W, Klase Z, Even Y, et al. CDK13, a new potential human immunodeficiency virus type 1 inhibitory factor regulating viral mRNA splicing. Journal of virology. 2008;82(14):7155-66.
48. Agbottah E, Yeh WI, Berro R, Klase Z, Pedati C, Kehn-Hall K, et al. Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. AIDS research and therapy. 2008;5:12.
49. Lee J, Klase Z, Gao X, Caldwell JS, Stinski MF, Kashanchi F, et al. Cellular homeoproteins, SATB1 and CDP, bind to the unique region between the human cytomegalovirus UL127 and major immediate-early genes. Virology. 2007;366(1):117-25.
50. Klase Z, Kale P, Winograd R, Gupta MV, Heydarian M, Berro R, et al. HIV-1 TAR element is processed by Dicer to yield a viral micro-RNA involved in chromatin remodeling of the viral LTR. BMC molecular biology. 2007;8:63.
51. Kehn K, Berro R, Alhaj A, Bottazzi M, Yeh W, Klase Z, et al. Functional consequences of cyclin D1/BRCA1 interaction in breast cancer cells. Oncogene. 2007;26(35):5060-9.
52. Berro R, de la Fuente C, Klase Z, Kehn K, Parvin L, Pumfery A, et al. Identifying the membrane proteome of HIV-1 latently infected cells. Journal of Biological Chemistry. 2007;282(11):8207-18.
53. Klase Z, Donio MJ, Blauvelt A, Marx PA, Jeang KT, Smith SM. A peptide-loaded dendritic cell based cytotoxic T-lymphocyte (CTL) vaccination strategy using peptides that span SIV Tat, Rev, and Env overlapping reading frames. Retrovirology. 2006;3:1.
54. de la Fuente C, Gupta MV, Klase Z, Strouss K, Cahan P, McCaffery T, et al. Involvement of HTLV-I Tax and CREB in aneuploidy: a bioinformatics approach. Retrovirology. 2006;3(1):43.
55. Ammosova T, Berro R, Jerebtsova M, Jackson A, Charles S, Klase Z, et al. Phosphorylation of HIV-1 Tat by CDK2 in HIV-1 transcription. Retrovirology. 2006;3(1):78.
56. Smith SM, Mefford M, Sodora D, Klase Z, Singh M, Alexander N, et al. Topical estrogen protects against SIV vaginal transmission without evidence of systemic effect. AIDS. 2004;18(12):1637-43.
57. Smith SM, Pentlicky S, Klase Z, Singh M, Neuveut C, Lu CY, et al. An in vivo replication-important function in the second coding exon of Tat is constrained against mutation despite cytotoxic T lymphocyte selection. The Journal of biological chemistry. 2003;278(45):44816-25.